"Ten Commandments" for Conducting Comparative Effectiveness Research Using "Real-World Data"

Examination of Data, Analytical Issues and Proposed Methods for Conducting Comparative Effectiveness Research Using “Real-World Data”

BACKGROUND: The Patient Protection and Affordable Care Act brought considerable attention to comparative effectiveness research (CER). OBJECTIVES: To (a) suggest best practices for conducting and reporting CER using “real-world data” (RWD), (b) describe some of the data and infrastructure requirements for conducting CER using RWD, (c) identify statistical challenges with the analysis of nonrand...

The Ten Commandments.

Ten commandments for implementing clinical information systems.

Ten commandments of enzymology, amended.

Reflections on advances and retreats in biochemistry have, over the years, generated several maxims. The late Efraim Racker’s ‘don’t waste clean thinking on dirty enzymes’ has been one of the most durable. On the occasion of a lecture in Jerusalem a decade ago, I framed a list of the ten ‘best’ maxims as ‘commandments’, which were later published as a ‘Guest Commentary’ in the Journal of Bacter...

Ten Commandments for patient-centred treatment

1. Thou shalt have no aim except to help patients, according to the goals they wish to achieve When deciding on a treatment, the first diagnosis you need to reach is about the nature of the illness. The second diagnosis you need concerns what the individual would like to achieve.1 Both are of equal importance and this is as true in simple one-off encounters as in complex lifelong illness. But t...